SANBORN (Ancestors and descendants of Lieut. John Sanborn (c. 1620 - 1692) of Hampton)
SANFORD (Ancestors and descendants of John Sanford)
SARGEANT (Descendants of William Sargeant (d. aft. 1670/1) of Salisbury and Amesbury)
SCHOU (Descendants of Frederich Schou of Kyndeløse, Denmark )
SCOTT (Descendants of Thomas Scott (bp. 1595) of Rattlesdon and Ipswich)
SCRIPTURE (Descendants of Samuel Scripture (d. 1738/42) of Groton)
SEARS (Descendants of Richard Sears)
SHEAFE (Ancestors of Dorothy Sheafe, wife of Rev. Henry Whitfield)
SIBERT (Descendants of John David Sibert of South Carolina)
SIMONDS (Descendants of William Simonds (d. 1672) of Woburn)
SLOCUM (Ancestors and descendants of Capt. Simon Slocum of Boston)
SMITH (Descendants of Hugh Smith)
SMITH (Descendants of Thomas Smith of Calvert county, Maryland)
SMITH (Descendants of Ens. Moses Smith of Chesterfield)
SMITH (Descendants of Lieut.Samuel Smith of Hatfield)
SPALDING (Descendants of Edward Spalding (d. 1669) of Chelmsford)
SPARROW (Descendants of Richard Sparrow of Eastham)
SPOFFORD (Descendants of Samuel Spofford)
SPURR (Descendants of Edward Spurr (c. 1610 - 1693) of Dorchester)
SQUIRE (Descendants of John Squire of Cambridge)
STACY (Descendants of Elizabeth (Unknown) Stacy (d. bef. 1670))
STEARNS (Descendants of Isaac Stearns of Watertown)
STICKNEY (Descendants of William Stickney (1592 - 1665) of Rowley)
STOCKBRIDGE (Descendants of John Stockbridge (abt 1608 - 1657) of Scituate and Boston)
SYMONDS (Descendants of John Symonds (abt 1595 - 1671) of Great Yarmouth and Salem)